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Richard Lin

M.D., University of California, San Francisco, 1988
Biology of Phosphoinositide 3-Kinases

Basic Science Tower, T-6, Room 180
Stony Brook University
Stony Brook, NY, 11794-8661

Phone: (631) 444-1638
Email: Richard.Lin@sunysb.edu



Biology of Phosphoinositide 3-Kinases

The research effort focuses on understanding the physiological functions and pathological roles of phosphoinositide 3-kinases (PI3Ks). These lipid kinases produce the intracellular second messenger phosphatidylinositol 3,4,5-trisphosphate that regulates diverse biological functions, including insulin action, neutrophil chemotaxis, and cell growth, proliferation and death. One major emphasis in this laboratory is to elucidate how individual PI3K catalytic isoforms regulate the contractile function and electrical properties of cardiac myocytes. Another major focus of the laboratory is to investigate how PI3Ks are involved in the development of pancreatic cancer. Other projects concern how PI3Ks control cellular and organismal metabolism.

Selected Publications

Dr. Lin's publications may be found at the following NCBI link::





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