M.Z. Cabail, S. Li, E. Lemmon, M.E. Bowen, S.R. Hubbard, and W.T. Miller (2015). The insulin and IGF1 receptor kinase domains are functional dimers in the activated state. Nature Communications 6., 6406.
K.P. Schultheiss, B.P. Craddock, H. Suga, and W.T. Miller (2014). Regulation of Src and Csk nonreceptor tyrosine kinases in the filasterean Ministeria vibrans. Biochemistry 53, 1320-1329.
H. Krishnan, J.A. Ochoa-Alvarez, Y. Shen, E. Nevel, M. Lakshminarayanan, M.C. Williams, M.I. Ramirez, W.T. Miller, and G.S. Goldberg (2013). Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility. J. Biol. Chem 288, 12215-12221.
K.P. Schultheiss, B.P. Craddock, M. Tong, M. Seeliger, and W.T. Miller (2013). Metazoan-like signaling in a unicellular receptor tyrosine kinase. BMC Biochem.14: 4.
B.P. Craddock and W.T. Miller (2012). Effects of somatic mutations in the C-terminus of insulin-like growth factor 1 receptor on activity and signaling.J. Signal Trans.804801.
W.T. Miller (2012). Tyrosine kinase signaling and the emergence of multicellularity. Biochim Biophys Acta 1823, 1053-7.
K.P. Schultheiss, H. Suga, I. Ruiz-Trillo, and W.T. Miller (2012). Lack of Csk-mediated negative regulation in a unicellular Src kinase. Biochemistry 51, 8267-8277.
V. Prieto-Echagüe, A. Gucwa, B.P. Craddock, D.A. Brown, and W.T. Miller (2010). Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. J. Biol. Chem. 285, 10605-10615.
V. Prieto-Echagüe, A. Gucwa, D.A. Brown, and W.T. Miller (2010). Regulation of Ack1 localization and activity by the amino-terminal SAM domain. BMC Biochemistry 11, 42.
W. Li, S. Scarlata, and W.T. Miller (2009). Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase. Biochemistry 48, 5180-5186.
P. Patwardhan, K. Shiba, C. Gordon, B.P. Craddock, M. Tamiko, and W.T. Miller (2009). Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs. ACS Chem. Biol 4, 751-758.
S.S. Yadav, B.J. Yeh, B.P. Craddock, W.A. Lim, and W.T. Miller (2009). Reengineering the signaling properties of a Src family kinase. Biochemistry 48, 10956-10962.
W.T. Miller (2009). Making sense of signal transduction. Science Signaling 2, pe79.
N. King, M.J. Westbrook, S.L. Young, et al (2008). The genome of the choanoflagellate Monosiga brevicollis and the origins of metazoans. Nature 451,783-788.
W. Li, S.L. Young, N. King, and W.T. Miller (2008). Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. J. Biol. Chem. 283, 15491-15501.
G. Manning, S.L. Young, W.T. Miller, and Y. Zhai (2008). The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any metazoan. Proc. Natl. Acad. Sci. USA. 105, 9674-9679.
J. Wu, W. Li, B.P. Craddock, K.W. Foreman, M.J. Mulvihill, Q.Ji, W.T. Miller, and S.R. Hubbard (2008). Small-molecule inhibition and activation loop trans-autophosphorylation of the IGF1 receptor. EMBO Journal. 27, 1985-1994.
B. Xiang, K. Chatti, H. Qiu, B. Lakshmi, A. Krasnitz, J. Hicks, W.T. Miller, and S.K. Muthuswamy (2008). Brk is coamplified with ErbB2 to promote proliferation in breast cancer. Proc. Natl. Acad. Sci. USA. 105, 12463-12468.
S.S. Yadav and W.T. Miller (2008). The evolutionarily conserved arrangement of domains in Src family kinases is important for substrate recognition. Biochemistry 47, 10871-10880.
P. Patwardhan and W.T. Miller (2007). Processive phosphorylation: mechanism and biological importance. Cell Signal. 19, 2218-2226.
H. Chen, J. Ma, W. Li, A.V. Eliseenkova, C. Xu, T.A. Neubert, W.T. Miller, and M. Mohammadi (2007). A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Molecular Cell. 27, 717-730.
S.R. Hubbard and W.T. Miller (2007). Receptor tyrosine kinases: mechanisms of activation and signaling. Curr. Opin. Cell Biol. 19, 117-123.