Publications 1994-1999

    J.H. Till, R.S. Annan, S.A. Carr, and W.T. Miller (1994) Use of Synthetic Peptide Libraries and Phosphopeptide-selective Mass Spectrometry to Probe Protein Kinase Substrate Specificity. J. Biol. Chem. 269, 7423-7428.

    P. Garcia, S.E. Shoelson, J.S. Drew, and W.T. Miller (1994). Phosphopeptide Occupancy and Photoaffinity Cross-linking of the v-Src SH2 Domain Attenuates Tyrosine Kinase Activity. J. Biol. Chem. 269, 30574-30579.

    J. Gergel, D.J. McNamara, E.M. Dobrusin, A.R. Saltiel, and W.T. Miller (1994). Identification of Amino Acid Residues in the Phospholipase Cg1 SH2 Domain which Interact with the Epidermal Growth Factor Receptor. Biochemistry 33, 14671-14678.

    T.R. Lee, J.H. Till, D.S. Lawrence, and W.T. Miller (1995). Precision Substrate Targeting of Protein Kinases: v-Abl and c-Src. J. Biol. Chem. 270, 27022-27026.

    B. Xu, V.G. Bird, and W.T. Miller (1995). Substrate Specificities of the Insulin and Insulin-like Growth Factor I Receptor Tyrosine Kinase Catalytic Domains. J. Biol. Chem.270, 29825-29830.

    W.T. Miller and D.P. Raleigh (1995). Protein Folding: From Basic Science to Biotechnology. Genetic Analysis 12, 169-172.

    Z.-Y. Zhang, A.B. Walsh, L. Wu, D.J. McNamara, E.M. Dobrusin, and W.T. Miller (1996). Determinants of Substrate Recognition in the Protein-Tyrosine Phosphatase, PTP1. J. Biol. Chem. 271, 5386-5392.

    X. Bin and W.T. Miller (1996). Src Homology Domains of v-Src Stabilize an Active Conformation of the Tyrosine Kinase Catalytic Domain. Mol. Cell. Biochem. 158, 57-63.

    P. Chan, P.R. Keller, R.W. Connors, W.R. Leopold, and W. T. Miller (1996). Amino-terminal Sequence Determinants for Substrate Recognition by Platelet-Derived Growth Factor Receptor Tyrosine Kinase. FEBS Lett. 394, 121-125.

    P. Pellicena, J. Scholten, K. Zimmerman, M. Creswell, C.C. Huang, and W.T. Miller (1996). Involvement of the Alpha Subunit of Farnesyl-Protein Transferase in Substrate Recognition. Biochemistry 35 , 13494 - 13500.

    J.E.A. Michaels, P. Schimmel, K. Shiba, and W.T. Miller (1996). Dominant Negative Inhibition by Polypeptide Fragments of a Monomeric Enzyme. Proc. Natl. Acad. Sci. USA 93, 14452-14455.

    I. Moarefi, M. LaFevre-Bernt, F. Sicheri, M. Huse, C.-H. Lee, J. Kuriyan, and W.T. Miller (1997). Activation of the Src-Family Tyrosine Kinase Hck by SH3 Domain Displacement. Nature 385, 650-653.

    P. Chan and W.T. Miller (1998). Use of Peptide Libraries to Determine Optimal Substrates of Tyrosine Kinases. Methods Mol. Biol. 84, 75-86.

    P. Pellicena, K.R. Stowell, and W.T. Miller (1998). Enhanced Phosphorylation of Src-family Kinase Substrates Containing SH2 Domain Binding Sites. J. Biol. Chem. 273, 15325-15328.

    H. Bayley, C. Chang, W.T. Miller, B. Niblack, and P. Pan (1998). Caged Peptides and Proteins by Targeted Chemical Modification. Methods Enz. 291, 117-135.

    M. LaFevre-Bernt, J. Corbin, S. Francis, and W.T. Miller (1998). Phosphorylation and Activation of cGMP-dependent Protein Kinase by v-Src. Biochim. Biophys. Acta 1386, 97-105.

    M. LaFevre-Bernt, F. Sicheri, A. Pico, M. Porter, J. Kuriyan, and W.T. Miller (1998). Intramolecular Regulatory Interactions in the Src-family Kinase Hck Probed by Mutagenesis of a Conserved Tryptophan Residue. J. Biol. Chem. 273, 32129-32134.

    J.E.A. Michaels, K. Shiba, and W.T. Miller (1999). Autonomous folding of a C-terminal inhibitory fragment of E. coli isoleucine-tRNA synthetase. Biochim. Biophys. Acta 1433, 103-109.

   N. Yokoyama and W.T. Miller (1999). Identification of residues involved in v-Src substrate recognition by site-directed mutagenesis. FEBS Lett. 456, 403-408.

    J.H. Till, P.M. Chan, and W.T. Miller (1999).  Engineering the Substrate Specificity of the Abl Tyrosine Kinase.  J. Biol. Chem. 274, 4995-5003.